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Unbiased estimation of biomarker panel performance when combining training and testing data in a group sequential design
Motivated by an ongoing study to develop a screening test able to identify patients with undiagnosed Sjögren’s Syndrome in a symptomatic population, we propose methodology to combine multiple biomarkers and evaluate their performance in a two-stage group sequential design that proceeds as follows: b...
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| Publicado no: | Biometrics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4974170/ https://ncbi.nlm.nih.gov/pubmed/26845527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12480 |
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