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Two-stage biomarker panel study and estimation allowing early termination for futility
Technological advances have yielded a wealth of biomarkers that have the potential to detect chronic diseases such as cancer. However, most biomarkers considered for further validation turn out not to have strong enough performance to be used in clinical practice. Group sequential designs that allow...
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| Publicado no: | Biostatistics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4570581/ https://ncbi.nlm.nih.gov/pubmed/25964662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxv017 |
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