Fibroblast Growth Factor 21 Limits Lipotoxicity by Promoting Hepatic Fatty Acid Activation in Mice on Methionine and Choline-deficient Diets

BACKGROUND & AIMS: Nonalcoholic fatty liver disease (NAFLD) is a common consequence of human and rodent obesity. Disruptions in lipid metabolism lead to accumulation of triglycerides and fatty acids, which can promote inflammation and fibrosis and lead to nonalcoholic steatohepatitis (NASH). Cir...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Gastroenterology
Autori principali: Fisher, ffolliott M., Chui, Patricia C., Nasser, Imad A., Popov, Yury, Cunniff, Jeremy C., Lundasen, Thomas, Kharitonenkov, Alexei, Schuppan, Detlef, Flier, Jeffrey S., Maratos-Flier, Eleftheria
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570569/
https://ncbi.nlm.nih.gov/pubmed/25083607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.07.044
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi