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Engineering trypsin for inhibitor resistance
The development of effective protease therapeutics requires that the proteases be more resistant to naturally occurring inhibitors while maintaining catalytic activity. A key step in developing inhibitor resistance is the identification of key residues in protease-inhibitor interaction. Given that m...
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| Publicado en: | Protein Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4570540/ https://ncbi.nlm.nih.gov/pubmed/26106067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2732 |
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