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Comparison of topological clustering within protein networks using edge metrics that evaluate full sequence, full structure, and active site microenvironment similarity

The development of accurate protein function annotation methods has emerged as a major unsolved biological problem. Protein similarity networks, one approach to function annotation via annotation transfer, group proteins into similarity-based clusters. An underlying assumption is that the edge metri...

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Detalles Bibliográficos
Publicado en:Protein Sci
Main Authors: Leuthaeuser, Janelle B, Knutson, Stacy T, Kumar, Kiran, Babbitt, Patricia C, Fetrow, Jacquelyn S
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Ltd 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570537/
https://ncbi.nlm.nih.gov/pubmed/26073648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2724
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