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Fbxw7 suppresses cancer metastasis by inhibiting niche formation
Fbxw7 has been identified as an oncosuppressor protein in many types of cancer. We have recently shown that loss of Fbxw7 in bone marrow-derived stromal cells (BMSCs) promotes cancer metastasis by increasing production of the chemokine CCL2, which attracts monocytic myeloid-derived suppressor cells...
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| Veröffentlicht in: | Oncoimmunology |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4570111/ https://ncbi.nlm.nih.gov/pubmed/26405580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1022308 |
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