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Degradation of the endoplasmic reticulum–anchored transcription factor MyRF by the ubiquitin ligase SCF(Fbxw7) in a manner dependent on the kinase GSK-3
The ubiquitin-proteasome system regulates the abundance of many cellular proteins by mediating their targeted degradation. We previously developed a method—differential proteomics–based identification of ubiquitylation substrates (DiPIUS)—for the comprehensive identification of substrates for a give...
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| Published in: | J Biol Chem |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5900774/ https://ncbi.nlm.nih.gov/pubmed/29472293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000741 |
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