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Substrate Binding Promotes Formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3)) Protein Complex

The Skp1–Cul1–F-box protein (SCF) complex is one of the most well characterized types of ubiquitin ligase (E3), with the E3 activity of the complex being regulated in part at the level of complex formation. Fbxl3 is an F-box protein that is responsible for the ubiquitylation and consequent degradati...

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Autori principali: Yumimoto, Kanae, Muneoka, Tetsuya, Tsuboi, Tomohiro, Nakayama, Keiichi I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820910/
https://ncbi.nlm.nih.gov/pubmed/24085301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.511303
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