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Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways

BACKGROUND: It is widely recognized that deep inspiration (DI), either before methacholine (MCh) challenge (Bronchoprotection, BP) or after MCh challenge (Bronchodilation, BD) protects against this challenge in healthy individuals, but not in asthmatics. Sulforaphane, a dietary antioxidant and antii...

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Bibliographische Detailangaben
Veröffentlicht in:Respir Res
Hauptverfasser: Brown, Robert H., Reynolds, Curt, Brooker, Allison, Talalay, Paul, Fahey, Jed W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570035/
https://ncbi.nlm.nih.gov/pubmed/26369337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0253-z
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