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Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways

BACKGROUND: It is widely recognized that deep inspiration (DI), either before methacholine (MCh) challenge (Bronchoprotection, BP) or after MCh challenge (Bronchodilation, BD) protects against this challenge in healthy individuals, but not in asthmatics. Sulforaphane, a dietary antioxidant and antii...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Brown, Robert H., Reynolds, Curt, Brooker, Allison, Talalay, Paul, Fahey, Jed W.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570035/
https://ncbi.nlm.nih.gov/pubmed/26369337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0253-z
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