Keap1-Nrf2 Signaling: A Target for Cancer Prevention by Sulforaphane

Sulforaphane is a promising agent under preclinical evaluation in many models of disease prevention. This bioactive phytochemical affects many molecular targets in cellular and animal models; however, amongst the most sensitive is Keap1, a key sensor for the adaptive stress response system regulated...

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Bibliografiske detaljer
Main Authors: Kensler, Thomas W, Egner, Patricia A, Agyeman, Abena S., Visvanathan, Kala, Groopman, John D, Chen, Jian-Guo, Chen, Tao-Yang, Fahey, Jed W, Talalay, Paul
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553557/
https://ncbi.nlm.nih.gov/pubmed/22752583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/128_2012_339
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