Transcriptomic and Proteomic Profiling of KEAP1 Disrupted and Sulforaphane Treated Human Breast Epithelial Cells Reveals Common Expression Profiles

Sulforaphane (SFN), an isothiocyanate found in cruciferous vegetables, is a potent inhibitor of experimental mammary carcinogenesis and may be an effective, safe chemopreventive agent for use in humans. SFN acts in part on the Keap1/Nrf2 pathway to regulate a battery of cytoprotective genes. In this...

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Bibliografiske detaljer
Main Authors: Agyeman, Abena S., Chaerkady, Raghothama, Shaw, Patrick G., Davidson, Nancy E., Visvanathan, Kala, Pandey, Akhilesh, Kensler, Thomas W.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564494/
https://ncbi.nlm.nih.gov/pubmed/21597922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-011-1536-9
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