Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation

Although histone H3 lysine 27 trimethylation (H3K27Me3) is associated with gene silencing, whether H3K27Me3 demethylation affects transcription and cell differentiation in vivo has remained elusive. To investigate this, we conditionally inactivated the two H3K27Me3 demethylases, Jmjd3 and Utx, in no...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Manna, Sugata, Kim, Jong Kyong, Baugé, Catherine, Cam, Margaret, Zhao, Yongmei, Shetty, Jyoti, Vacchio, Melanie S., Castro, Ehydel, Tran, Bao, Tessarollo, Lino, Bosselut, Rémy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Pub. Group 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569738/
https://ncbi.nlm.nih.gov/pubmed/26328764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9152
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