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Histone demethylases in physiology and cancer: A tale of two enzymes, JMJD3 and UTX
Gene regulation is fine-tuned by a dynamic balance between transcriptionally activating and repressive modifications of histone tails. It has been well-established that lysine and arginine methylation can be reversed by two groups of evolutionarily conserved enzymes known as histone demethylases, wh...
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| Veröffentlicht in: | Curr Opin Genet Dev |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4880520/ https://ncbi.nlm.nih.gov/pubmed/27151432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2016.03.010 |
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