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Histone demethylases in physiology and cancer: A tale of two enzymes, JMJD3 and UTX

Gene regulation is fine-tuned by a dynamic balance between transcriptionally activating and repressive modifications of histone tails. It has been well-established that lysine and arginine methylation can be reversed by two groups of evolutionarily conserved enzymes known as histone demethylases, wh...

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Detalhes bibliográficos
Publicado no:Curr Opin Genet Dev
Main Authors: Arcipowski, Kelly Marie, Martinez, Carlos Alberto, Ntziachristos, Panagiotis
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880520/
https://ncbi.nlm.nih.gov/pubmed/27151432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2016.03.010
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