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Mechanistic asymmetry in Hsp90 dimers
Hsp90 is a molecular chaperone that facilitates the maturation of signaling proteins including many kinases and steroid hormone receptors. Through these client proteins, Hsp90 is a key mediator of many physiological processes and has emerged as a promising drug target in cancer. Additionally, Hsp90...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4569507/ https://ncbi.nlm.nih.gov/pubmed/25843003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.03.017 |
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