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Tumstatin 185-191 increases the sensitivity of non-small cell lung carcinoma cells to cisplatin by blocking proliferation, promoting apoptosis and inhibiting Akt activation

Purpose: This study aimed to investigate the synergistic anti-tumor effects of tumstatin 185-191 and cisplatin in non-small cell lung carcinoma cells (NSCLC) (A549 cells and cisplatin resistant A549/DDP cells), and the potential role of Akt signaling pathway was also explored. Methods: A549 or A549/...

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Bibliografske podrobnosti
izdano v:Am J Transl Res
Main Authors: Wang, Wei, Chen, Ping, Tang, Min, Li, Junli, Pei, Yanfang, Cai, Shan, Zhou, Xiao, Chen, Senlin
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568790/
https://ncbi.nlm.nih.gov/pubmed/26396665
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