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Velocities of unloaded muscle filaments are not limited by drag forces imposed by myosin cross-bridges
It is not known which kinetic step in the acto-myosin ATPase cycle limits contraction speed in unloaded muscles (V(0)). Huxley’s 1957 model [Huxley AF (1957) Prog Biophys Biophys Chem 7:255–318] predicts that V(0) is limited by the rate that myosin detaches from actin. However, this does not explain...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4568697/ https://ncbi.nlm.nih.gov/pubmed/26294254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510241112 |
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