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Velocities of unloaded muscle filaments are not limited by drag forces imposed by myosin cross-bridges

It is not known which kinetic step in the acto-myosin ATPase cycle limits contraction speed in unloaded muscles (V(0)). Huxley’s 1957 model [Huxley AF (1957) Prog Biophys Biophys Chem 7:255–318] predicts that V(0) is limited by the rate that myosin detaches from actin. However, this does not explain...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Brizendine, Richard K., Alcala, Diego B., Carter, Michael S., Haldeman, Brian D., Facemyer, Kevin C., Baker, Josh E., Cremo, Christine R.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568697/
https://ncbi.nlm.nih.gov/pubmed/26294254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510241112
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