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Positive and Negative Regulatory Mechanisms for Fine-Tuning Cellularity and Functions of Medullary Thymic Epithelial Cells

Self-tolerant T cells and regulatory T cells develop in the thymus. A wide variety of cell–cell interactions in the thymus is required for the differentiation, proliferation, and repertoire selection of T cells. Various secreted and cell surface molecules expressed in thymic epithelial cells (TECs)...

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Vydáno v:Front Immunol
Hlavní autoři: Akiyama, Taishin, Tateishi, Ryosuke, Akiyama, Nobuko, Yoshinaga, Riko, Kobayashi, Tetsuya J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568481/
https://ncbi.nlm.nih.gov/pubmed/26441966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00461
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