Hypergravity Provokes a Temporary Reduction in CD4+CD8+ Thymocyte Number and a Persistent Decrease in Medullary Thymic Epithelial Cell Frequency in Mice

Gravity change affects many immunological systems. We investigated the effects of hypergravity (2G) on murine thymic cells. Exposure of mice to 2G for three days reduced the frequency of CD4(+)CD8(+) thymocytes (DP) and mature medullary thymic epithelial cells (mTECs), accompanied by an increment of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tateishi, Ryosuke, Akiyama, Nobuko, Miyauchi, Maki, Yoshinaga, Riko, Sasanuma, Hiroki, Kudo, Takashi, Shimbo, Miki, Shinohara, Masahiro, Obata, Koji, Inoue, Jun-ichiro, Shirakawa, Masaki, Shiba, Dai, Asahara, Hiroshi, Yoshida, Nobuaki, Takahashi, Satoru, Morita, Hironobu, Akiyama, Taishin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626100/
https://ncbi.nlm.nih.gov/pubmed/26513242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141650
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