Hypergravity Provokes a Temporary Reduction in CD4+CD8+ Thymocyte Number and a Persistent Decrease in Medullary Thymic Epithelial Cell Frequency in Mice

Gravity change affects many immunological systems. We investigated the effects of hypergravity (2G) on murine thymic cells. Exposure of mice to 2G for three days reduced the frequency of CD4(+)CD8(+) thymocytes (DP) and mature medullary thymic epithelial cells (mTECs), accompanied by an increment of...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Tateishi, Ryosuke, Akiyama, Nobuko, Miyauchi, Maki, Yoshinaga, Riko, Sasanuma, Hiroki, Kudo, Takashi, Shimbo, Miki, Shinohara, Masahiro, Obata, Koji, Inoue, Jun-ichiro, Shirakawa, Masaki, Shiba, Dai, Asahara, Hiroshi, Yoshida, Nobuaki, Takahashi, Satoru, Morita, Hironobu, Akiyama, Taishin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626100/
https://ncbi.nlm.nih.gov/pubmed/26513242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141650
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