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Mechanisms of Drug Resistance that Target the Androgen Axis in Castration Resistant Prostate Cancer (CRPC)
Castrate resistant prostate cancer (CRPC) is the fatal-form of prostate cancer and remains androgen dependent. The reactivation of the androgen axis occurs due to adaptive intratumoral androgen biosynthesis which can be driven by adrenal androgens and /or by changes in the androgen receptor (AR) inc...
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| Publicado no: | J Steroid Biochem Mol Biol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4568163/ https://ncbi.nlm.nih.gov/pubmed/26032458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2015.05.010 |
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