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Translational repression protects human keratinocytes from UVB-induced apoptosis through a discordant eIF2 kinase stress response

This study delineates the mechanisms by which ultraviolet B (UVB) regulates protein synthesis in human keratinocytes and the importance of translational control in cell survival. Translation initiation is regulated by phosphorylation of eukaryotic initiation factor 2 (eIF2~P), which causes decreased...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Collier, Ann E., Wek, Ronald C., Spandau, Dan F
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567905/
https://ncbi.nlm.nih.gov/pubmed/25950825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.177
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