Streptolysin S Promotes Programmed Cell Death and Enhances Inflammatory Signaling in Epithelial Keratinocytes during Group A Streptococcus Infection

Streptococcus pyogenes, or group A Streptococcus (GAS), is a pathogen that causes a multitude of human diseases from pharyngitis to severe infections such as toxic shock syndrome and necrotizing fasciitis. One of the primary virulence factors produced by GAS is the peptide toxin streptolysin S (SLS)...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Flaherty, Rebecca A., Puricelli, Jessica M., Higashi, Dustin L., Park, Claudia J., Lee, Shaun W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567650/
https://ncbi.nlm.nih.gov/pubmed/26238711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00611-15
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