Streptolysin S Promotes Programmed Cell Death and Enhances Inflammatory Signaling in Epithelial Keratinocytes during Group A Streptococcus Infection

Streptococcus pyogenes, or group A Streptococcus (GAS), is a pathogen that causes a multitude of human diseases from pharyngitis to severe infections such as toxic shock syndrome and necrotizing fasciitis. One of the primary virulence factors produced by GAS is the peptide toxin streptolysin S (SLS)...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Flaherty, Rebecca A., Puricelli, Jessica M., Higashi, Dustin L., Park, Claudia J., Lee, Shaun W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567650/
https://ncbi.nlm.nih.gov/pubmed/26238711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00611-15
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