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Streptolysin S Promotes Programmed Cell Death and Enhances Inflammatory Signaling in Epithelial Keratinocytes during Group A Streptococcus Infection

Streptococcus pyogenes, or group A Streptococcus (GAS), is a pathogen that causes a multitude of human diseases from pharyngitis to severe infections such as toxic shock syndrome and necrotizing fasciitis. One of the primary virulence factors produced by GAS is the peptide toxin streptolysin S (SLS)...

Полное описание

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Библиографические подробности
Опубликовано в: :Infect Immun
Главные авторы: Flaherty, Rebecca A., Puricelli, Jessica M., Higashi, Dustin L., Park, Claudia J., Lee, Shaun W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567650/
https://ncbi.nlm.nih.gov/pubmed/26238711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00611-15
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