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Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins

Iron regulatory proteins 1 and 2 (IRP1 and IRP2) are two cytosolic proteins that maintain cellular iron homeostasis by binding to RNA stem loops known as iron responsive elements (IREs) that are found in the untranslated regions of target mRNAs that encode proteins involved in iron metabolism. IRPs...

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Foilsithe in:Neurobiol Dis
Main Authors: Ghosh, Manik C., Zhang, De-Liang, Rouault, Tracey A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567523/
https://ncbi.nlm.nih.gov/pubmed/25771171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.02.026
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