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Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins

Iron regulatory proteins 1 and 2 (IRP1 and IRP2) are two cytosolic proteins that maintain cellular iron homeostasis by binding to RNA stem loops known as iron responsive elements (IREs) that are found in the untranslated regions of target mRNAs that encode proteins involved in iron metabolism. IRPs...

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Podrobná bibliografie
Vydáno v:Neurobiol Dis
Hlavní autoři: Ghosh, Manik C., Zhang, De-Liang, Rouault, Tracey A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567523/
https://ncbi.nlm.nih.gov/pubmed/25771171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.02.026
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