A G-quadruplex-binding macrodomain within the “SARS-unique domain” is essential for the activity of the SARS-coronavirus replication–transcription complex

The multi-domain non-structural protein 3 of SARS-coronavirus is a component of the viral replication/transcription complex (RTC). Among other domains, it contains three sequentially arranged macrodomains: the X domain and subdomains SUD-N as well as SUD-M within the “SARS-unique domain”. The X doma...

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Bibliographische Detailangaben
Veröffentlicht in:Virology
Hauptverfasser: Kusov, Yuri, Tan, Jinzhi, Alvarez, Enrique, Enjuanes, Luis, Hilgenfeld, Rolf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Inc. 2015
Schlagworte:
Brief Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567502/
https://ncbi.nlm.nih.gov/pubmed/26149721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.06.016
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