The SARS-Unique Domain (SUD) of SARS Coronavirus Contains Two Macrodomains That Bind G-Quadruplexes

Since the outbreak of severe acute respiratory syndrome (SARS) in 2003, the three-dimensional structures of several of the replicase/transcriptase components of SARS coronavirus (SARS-CoV), the non-structural proteins (Nsps), have been determined. However, within the large Nsp3 (1922 amino-acid resi...

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Detalhes bibliográficos
Main Authors: Tan, Jinzhi, Vonrhein, Clemens, Smart, Oliver S., Bricogne, Gerard, Bollati, Michela, Kusov, Yuri, Hansen, Guido, Mesters, Jeroen R., Schmidt, Christian L., Hilgenfeld, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674928/
https://ncbi.nlm.nih.gov/pubmed/19436709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000428
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