Eosinophils and IL-33 perpetuate chronic inflammation and fibrosis in a pediatric population with stricturing Crohn’s ileitis

BACKGROUND: Fibrostenosis and stricture are well-recognized endpoints in Crohn’s disease (CD). We hypothesized that stricturing-CD is characterized by eosinophilia and epithelial-IL-33. We proposed that eosinophil exposure to IL-33 would perpetuate inflammatory chronicity and subsequent fibrostenosi...

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Detaylı Bibliyografya
Yayımlandı:Inflamm Bowel Dis
Asıl Yazarlar: Masterson, Joanne C., Capocelli, Kelley E., Hosford, Lindsay, Biette, Kathryn, McNamee, Eóin N., de Zoeten, Edwin F, Harris, Rachel, Fernando, Shahan D., Jedlicka, Paul, Protheroe, Cheryl, Lee, James J., Furuta, Glenn T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567482/
https://ncbi.nlm.nih.gov/pubmed/26218140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000512
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