Local hypersensitivity reaction in transgenic mice with squamous epithelial IL-5 overexpression provides a novel model of eosinophilic oesophagitis

OBJECTIVE: Eosinophilic oesophagitis (EoE) is a chronic inflammatory condition of the oesophagus with limited treatment options. No previous transgenic model has specifically targeted the oesophageal mucosa to induce oesophageal eosinophilia. DESIGN: We developed a mouse model that closely resembles...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Masterson, Joanne C, McNamee, Eóin N, Hosford, Lindsay, Capocelli, Kelley E, Ruybal, Joseph, Fillon, Sophie A, Doyle, Alfred D, Eltzschig, Holger K, Rustgi, Anil K, Protheroe, Cheryl A, Lee, Nancy A, Lee, James J, Furuta, Glenn T
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884674/
https://ncbi.nlm.nih.gov/pubmed/23161496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2012-303631
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