Local hypersensitivity reaction in transgenic mice with squamous epithelial IL-5 overexpression provides a novel model of eosinophilic oesophagitis

OBJECTIVE: Eosinophilic oesophagitis (EoE) is a chronic inflammatory condition of the oesophagus with limited treatment options. No previous transgenic model has specifically targeted the oesophageal mucosa to induce oesophageal eosinophilia. DESIGN: We developed a mouse model that closely resembles...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Masterson, Joanne C, McNamee, Eóin N, Hosford, Lindsay, Capocelli, Kelley E, Ruybal, Joseph, Fillon, Sophie A, Doyle, Alfred D, Eltzschig, Holger K, Rustgi, Anil K, Protheroe, Cheryl A, Lee, Nancy A, Lee, James J, Furuta, Glenn T
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2012
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884674/
https://ncbi.nlm.nih.gov/pubmed/23161496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2012-303631
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