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Eosinophils and IL-33 perpetuate chronic inflammation and fibrosis in a pediatric population with stricturing Crohn’s ileitis
BACKGROUND: Fibrostenosis and stricture are well-recognized endpoints in Crohn’s disease (CD). We hypothesized that stricturing-CD is characterized by eosinophilia and epithelial-IL-33. We proposed that eosinophil exposure to IL-33 would perpetuate inflammatory chronicity and subsequent fibrostenosi...
में बचाया:
में प्रकाशित: | Inflamm Bowel Dis |
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मुख्य लेखकों: | , , , , , , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2015
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4567482/ https://ncbi.nlm.nih.gov/pubmed/26218140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000512 |
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