Eosinophils and IL-33 perpetuate chronic inflammation and fibrosis in a pediatric population with stricturing Crohn’s ileitis

BACKGROUND: Fibrostenosis and stricture are well-recognized endpoints in Crohn’s disease (CD). We hypothesized that stricturing-CD is characterized by eosinophilia and epithelial-IL-33. We proposed that eosinophil exposure to IL-33 would perpetuate inflammatory chronicity and subsequent fibrostenosi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Inflamm Bowel Dis
Main Authors: Masterson, Joanne C., Capocelli, Kelley E., Hosford, Lindsay, Biette, Kathryn, McNamee, Eóin N., de Zoeten, Edwin F, Harris, Rachel, Fernando, Shahan D., Jedlicka, Paul, Protheroe, Cheryl, Lee, James J., Furuta, Glenn T.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567482/
https://ncbi.nlm.nih.gov/pubmed/26218140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000512
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker