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Loss of marginal zone B-cells in SHIV(SF162P4) challenged Rhesus macaques despite control of viremia to low or undetectable levels in chronic infection
Marginal zone (MZ) B cells generate T-independent antibody responses to pathogens before T-dependent antibodies arise in germinal centers. They have been identified in cynomolgus monkeys and monitored during acute SIV infection, yet have not been well-studied in rhesus macaques. Here we characterize...
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Yayımlandı: | Virology |
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Asıl Yazarlar: | , , , , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2015
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4567457/ https://ncbi.nlm.nih.gov/pubmed/26151223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.06.022 |
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