Multiple Vaccine-Elicited Nonneutralizing Antienvelope Antibody Activities Contribute to Protective Efficacy by Reducing both Acute and Chronic Viremia following Simian/Human Immunodeficiency Virus SHIV(89.6P) Challenge in Rhesus Macaques

We have shown that following priming with replicating adenovirus type 5 host range mutant (Ad5hr)-human immunodeficiency virus (HIV)/simian immunodeficiency virus (SIV) recombinants, boosting with gp140 envelope protein enhances acute-phase protection against intravenous simian/human immunodeficienc...

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Detalhes bibliográficos
Main Authors: Xiao, Peng, Zhao, Jun, Patterson, L. Jean, Brocca-Cofano, Egidio, Venzon, David, Kozlowski, Pamela A., Hidajat, Rachmat, Demberg, Thorsten, Robert-Guroff, Marjorie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898229/
https://ncbi.nlm.nih.gov/pubmed/20444898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00410-10
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