Comparative study of Tat vaccine regimens in Mauritian cynomolgus and Indian rhesus macaques: influence of Mauritian MHC haplotypes on susceptibility/resistance to SHIV(89.6P) infection

Protection afforded by HIV Tat-based vaccines has differed in Indian rhesus and Mauritian cynomolgus macaques. We evaluated native Tat and Ad-HIVtat priming/Tat-boosting regimens in both species. Both vaccines were immunogenic. Only the Ad-tat regimen modestly reduced acute viremia in rhesus macaque...

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Huvudupphovsmän: Florese, Ruth H., Wiseman, Roger W., Venzon, David, Karl, Julie A., Demberg, Thorsten, Larsen, Kay, Flanary, Leon, Kalyanaraman, V.S., Pal, Ranajit, Titti, Fausto, Patterson, L. Jean, Heath, Megan J., O’Connor, David H., Cafaro, Aurelio, Ensoli, Barbara, Robert-Guroff, Marjorie
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577850/
https://ncbi.nlm.nih.gov/pubmed/18486283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.03.100
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