Vaccine-elicited SIV and HIV envelope-specific IgA and IgG memory B cells in rhesus macaque peripheral blood correlate with functional antibody responses and reduced viremia

An effective HIV vaccine requires strong systemic and mucosal, cellular and humoral immunity. Numerous non-human primate studies have investigated memory T cells, but not memory B cells. Humoral immunologic memory is mediated by long-lived antibody-secreting plasma cells and differentiation of memor...

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Hlavní autoři: Brocca-Cofano, Egidio, McKinnon, Katherine, Demberg, Thorsten, Venzon, David, Hidajat, Rachmat, Xiao, Peng, Daltabuit-Test, Mara, Patterson, L. Jean, Robert-Guroff, Marjorie
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079049/
https://ncbi.nlm.nih.gov/pubmed/21382487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.02.066
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