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Purification and functional characterization of mucosal IgA from vaccinated and SIV-infected rhesus macaques

Vaccine-induced mucosal antibodies are often evaluated using small volumes of secretory fluids. However, fecal matter containing mucosal IgA is abundant. We purified fecal IgA from five SIV-vaccinated and five SIV-infected rhesus macaques by sequential affinity chromatography. The purified IgA was d...

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Detalhes bibliográficos
Publicado no:Clin Immunol
Main Authors: Musich, Thomas, Demberg, Thorsten, Morgan, Ian L., Estes, Jacob D., Franchini, Genoveffa, Robert-Guroff, Marjorie
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464970/
https://ncbi.nlm.nih.gov/pubmed/25840105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2015.03.020
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