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Comet assay measures of DNA damage as biomarkers of irinotecan response in colorectal cancer in vitro and in vivo
The use of irinotecan to treat metastatic colorectal cancer (CRC) is limited by unpredictable response and variable toxicity; however, no reliable clinical biomarkers are available. Here, we report a study to ascertain whether irinotecan-induced DNA damage measures are suitable/superior biomarkers o...
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| Publicado no: | Cancer Med |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4567016/ https://ncbi.nlm.nih.gov/pubmed/26108357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.477 |
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