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In Vivo Alkaline Comet Assay and Enzyme-modified Alkaline Comet Assay for Measuring DNA Strand Breaks and Oxidative DNA Damage in Rat Liver

Unrepaired DNA damage can lead to genetic instability, which in turn may enhance cancer development. Therefore, identifying potential DNA damaging agents is important for protecting public health. The in vivo alkaline comet assay, which detects DNA damage as strand breaks, is especially relevant for...

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Bibliografski detalji
Izdano u:J Vis Exp
Glavni autori: Ding, Wei, Bishop, Michelle E., Lyn-Cook, Lascelles E., Davis, Kelly J., Manjanatha, Mugimane G.
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942029/
https://ncbi.nlm.nih.gov/pubmed/27166647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53833
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