In Vivo Alkaline Comet Assay and Enzyme-modified Alkaline Comet Assay for Measuring DNA Strand Breaks and Oxidative DNA Damage in Rat Liver

Unrepaired DNA damage can lead to genetic instability, which in turn may enhance cancer development. Therefore, identifying potential DNA damaging agents is important for protecting public health. The in vivo alkaline comet assay, which detects DNA damage as strand breaks, is especially relevant for...

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書目詳細資料
發表在:J Vis Exp
Main Authors: Ding, Wei, Bishop, Michelle E., Lyn-Cook, Lascelles E., Davis, Kelly J., Manjanatha, Mugimane G.
格式: Artigo
語言:Inglês
出版: MyJove Corporation 2016
主題:
Molecular Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942029/
https://ncbi.nlm.nih.gov/pubmed/27166647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53833
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