In Vivo Alkaline Comet Assay and Enzyme-modified Alkaline Comet Assay for Measuring DNA Strand Breaks and Oxidative DNA Damage in Rat Liver

Unrepaired DNA damage can lead to genetic instability, which in turn may enhance cancer development. Therefore, identifying potential DNA damaging agents is important for protecting public health. The in vivo alkaline comet assay, which detects DNA damage as strand breaks, is especially relevant for...

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Vydáno v:J Vis Exp
Hlavní autoři: Ding, Wei, Bishop, Michelle E., Lyn-Cook, Lascelles E., Davis, Kelly J., Manjanatha, Mugimane G.
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2016
Témata:
Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942029/
https://ncbi.nlm.nih.gov/pubmed/27166647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53833
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