Elevated expression of periostin in human osteoarthritic cartilage and its potential role in matrix degradation via matrix metalloproteinase-13

We investigated the role of periostin, an extracellular matrix protein, in the pathophysiology of osteoarthritis (OA). In OA, dysregulated gene expression and phenotypic changes in articular chondrocytes culminate in progressive loss of cartilage from the joint surface. The molecular mechanisms unde...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Attur, Mukundan, Yang, Qing, Shimada, Kohei, Tachida, Yuki, Nagase, Hiroyuki, Mignatti, Paolo, Statman, Lauren, Palmer, Glyn, Kirsch, Thorsten, Beier, Frank, Abramson, Steven B.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566939/
https://ncbi.nlm.nih.gov/pubmed/26092928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-272427
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados