Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF

Fibrinogen, coagulation factor VII (FVII), and factor VIII (FVIII) and its carrier von Willebrand factor (vWF) play key roles in hemostasis. Previously identified common variants explain only a small fraction of the trait heritabilities, and additional variations may be explained by associations wit...

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Detaylı Bibliyografya
Yayımlandı:Blood
Asıl Yazarlar: Huffman, Jennifer E., de Vries, Paul S., Morrison, Alanna C., Sabater-Lleal, Maria, Kacprowski, Tim, Auer, Paul L., Brody, Jennifer A., Chasman, Daniel I., Chen, Ming-Huei, Guo, Xiuqing, Lin, Li-An, Marioni, Riccardo E., Müller-Nurasyid, Martina, Yanek, Lisa R., Pankratz, Nathan, Grove, Megan L., de Maat, Moniek P. M., Cushman, Mary, Wiggins, Kerri L., Qi, Lihong, Sennblad, Bengt, Harris, Sarah E., Polasek, Ozren, Riess, Helene, Rivadeneira, Fernando, Rose, Lynda M., Goel, Anuj, Taylor, Kent D., Teumer, Alexander, Uitterlinden, André G., Vaidya, Dhananjay, Yao, Jie, Tang, Weihong, Levy, Daniel, Waldenberger, Melanie, Becker, Diane M., Folsom, Aaron R., Giulianini, Franco, Greinacher, Andreas, Hofman, Albert, Huang, Chiang-Ching, Kooperberg, Charles, Silveira, Angela, Starr, John M., Strauch, Konstantin, Strawbridge, Rona J., Wright, Alan F., McKnight, Barbara, Franco, Oscar H., Zakai, Neil, Mathias, Rasika A., Psaty, Bruce M., Ridker, Paul M., Tofler, Geoffrey H., Völker, Uwe, Watkins, Hugh, Fornage, Myriam, Hamsten, Anders, Deary, Ian J., Boerwinkle, Eric, Koenig, Wolfgang, Rotter, Jerome I., Hayward, Caroline, Dehghan, Abbas, Reiner, Alex P., O’Donnell, Christopher J., Smith, Nicholas L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2015
Konular:
Thrombosis and Hemostasis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566813/
https://ncbi.nlm.nih.gov/pubmed/26105150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-02-624551
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