Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF

Fibrinogen, coagulation factor VII (FVII), and factor VIII (FVIII) and its carrier von Willebrand factor (vWF) play key roles in hemostasis. Previously identified common variants explain only a small fraction of the trait heritabilities, and additional variations may be explained by associations wit...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Blood
المؤلفون الرئيسيون: Huffman, Jennifer E., de Vries, Paul S., Morrison, Alanna C., Sabater-Lleal, Maria, Kacprowski, Tim, Auer, Paul L., Brody, Jennifer A., Chasman, Daniel I., Chen, Ming-Huei, Guo, Xiuqing, Lin, Li-An, Marioni, Riccardo E., Müller-Nurasyid, Martina, Yanek, Lisa R., Pankratz, Nathan, Grove, Megan L., de Maat, Moniek P. M., Cushman, Mary, Wiggins, Kerri L., Qi, Lihong, Sennblad, Bengt, Harris, Sarah E., Polasek, Ozren, Riess, Helene, Rivadeneira, Fernando, Rose, Lynda M., Goel, Anuj, Taylor, Kent D., Teumer, Alexander, Uitterlinden, André G., Vaidya, Dhananjay, Yao, Jie, Tang, Weihong, Levy, Daniel, Waldenberger, Melanie, Becker, Diane M., Folsom, Aaron R., Giulianini, Franco, Greinacher, Andreas, Hofman, Albert, Huang, Chiang-Ching, Kooperberg, Charles, Silveira, Angela, Starr, John M., Strauch, Konstantin, Strawbridge, Rona J., Wright, Alan F., McKnight, Barbara, Franco, Oscar H., Zakai, Neil, Mathias, Rasika A., Psaty, Bruce M., Ridker, Paul M., Tofler, Geoffrey H., Völker, Uwe, Watkins, Hugh, Fornage, Myriam, Hamsten, Anders, Deary, Ian J., Boerwinkle, Eric, Koenig, Wolfgang, Rotter, Jerome I., Hayward, Caroline, Dehghan, Abbas, Reiner, Alex P., O’Donnell, Christopher J., Smith, Nicholas L.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society of Hematology 2015
الموضوعات:
Thrombosis and Hemostasis
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566813/
https://ncbi.nlm.nih.gov/pubmed/26105150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-02-624551
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