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Expression of variant von Willebrand factor (vWF) cDNA in heterologous cells: requirement of the pro-polypeptide in vWF multimer formation.

Von Willebrand factor (vWF) is a multimeric plasma glycoprotein synthesized by vascular endothelial cells as a pre-pro-polypeptide with a highly repetitive domain structure, symbolized by the formula: (H)-D1-D2-D'-D3-A1-A2-A3-D4-B1-B2-B3-C1-C2-(OH) A heterologous expression system for the synth...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Verweij, C L, Hart, M, Pannekoek, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553722/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3500851/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb02591.x
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