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Stimulation of Respiratory Motor Output and Ventilation in a Murine Model of Pompe Disease by Ampakines
Pompe disease results from a mutation in the acid α-glucosidase gene leading to lysosomal glycogen accumulation. Respiratory insufficiency is common, and the current U.S. Food and Drug Administration–approved treatment, enzyme replacement, has limited effectiveness. Ampakines are drugs that enhance...
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| Publicado no: | Am J Respir Cell Mol Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Thoracic Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4566070/ https://ncbi.nlm.nih.gov/pubmed/25569118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0374OC |
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