Stimulation of Respiratory Motor Output and Ventilation in a Murine Model of Pompe Disease by Ampakines

Pompe disease results from a mutation in the acid α-glucosidase gene leading to lysosomal glycogen accumulation. Respiratory insufficiency is common, and the current U.S. Food and Drug Administration–approved treatment, enzyme replacement, has limited effectiveness. Ampakines are drugs that enhance...

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Bibliographic Details
Published in:Am J Respir Cell Mol Biol
Main Authors: ElMallah, Mai K., Pagliardini, Silvia, Turner, Sara M., Cerreta, Anthony J., Falk, Darin J., Byrne, Barry J., Greer, John J., Fuller, David D.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2015
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566070/
https://ncbi.nlm.nih.gov/pubmed/25569118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0374OC
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