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The Histone Deacetylase Inhibitor Vaproic Acid Induces Cell Growth Arrest in Hepatocellular Carcinoma Cells via Suppressing Notch Signaling

Hepatocellular carcinoma (HCC) is a type of malignant cancer. Notch signaling is aberrantly expressed in HCC tissues with more evidence showing that this signaling plays a critical role in HCCs. In the present study, we investigate the effects of the anti-convulsant drug valproic acid (VPA) in HCC c...

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Détails bibliographiques
Publié dans:J Cancer
Auteurs principaux: Sun, Guangchun, Mackey, Lily V., Coy, David H., Yu, Cui-Yun, Sun, Lichun
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565849/
https://ncbi.nlm.nih.gov/pubmed/26366213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.12135
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