Loading...
Histone deacetylase inhibitors upregulate Notch1 and inhibit growth in pheochromocytoma cells
BACKGROUND: The histone deacetylase (HDAC) inhibitors valproic acid (VPA) and suberoyl bis-hydroxamic acid (SBHA) have recently been demonstrated to be strong Notch1 activators. Upregulation of the Notch1 pathway has been shown to limit growth and suppress hormonal secretion in neuroendocrine (NE) t...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2638099/ https://ncbi.nlm.nih.gov/pubmed/19041003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2008.08.027 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|