Inhibition of growth in medullary thyroid cancer cells with histone deacetylase inhibitors and lithium chloride

BACKGROUND: While representing only 3% of thyroid malignancies, medullary thyroid cancer (MTC) accounts for 14% of thyroid cancer deaths. MTC has a high rate of recurrence and lacks effective treatments. The histone deacetylase (HDAC) inhibitors valproic acid (VPA) and suberoyl bis-hydroxamic acid (...

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Bibliografiska uppgifter
Huvudupphovsmän: Adler, Joel T., Hottinger, Daniel G., Kunnimalaiyaan, Muthusamy, Chen, Herbert
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858235/
https://ncbi.nlm.nih.gov/pubmed/19394967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2008.08.004
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